6 parts in 3 volumes, 4to (254 x 163 mm). 60 colored plates comprising 10 hand-colored copper engravings and 50 plates printed in color (offsetting, some minor losses to select plates.) 19th century half morocco, top edges gilt (rubbing to extremities).

FIRST EDITION of the first American book to employ color printing, developed by Bigelow via a new aqua-tint process. Work on American Medical Botany began shortly after Bigelow was appointed professor of materia medica at the Harvard Medical School. Austin 205; Bennett 11; Cushing B384; Garrison/Morton 1842; Nissen BBI 164; Norman 234; Pritzel 733; Reese, American Color Plate Books 9; Sabin 5294.